Opportunity Information: Apply for W81XWH 18 HRRP TRA
The DoD Hearing Restoration Translational Research Award (FY18 HRRP TRA; Funding Opportunity Number W81XWH 18 HRRP TRA) is a Department of Defense funding opportunity designed to push hearing restoration science out of the lab and into real-world clinical use. The program sits squarely in the translational space, meaning it is meant for projects that take credible, promising findings and actively move them toward applications that can be tested, validated, and ultimately used to improve patient care. Rather than funding purely exploratory basic science, the intent is to accelerate steps that help new hearing-related discoveries become healthcare products, enabling technologies, or evidence-based practice guidelines that clinicians can actually implement.
A central theme of this opportunity is that strong translational work can start from many kinds of observations, not just traditional bench discoveries. The Department of Defense explicitly recognizes that impactful research ideas may come from laboratory breakthroughs, population-level or epidemiologic studies, or practical clinical insights such as what clinicians see in patients and even well-grounded anecdotal experience. In other words, applicants are encouraged to treat patient needs and real clinical constraints as legitimate starting points for innovation, as long as the project is structured to convert those observations into something actionable and clinically relevant.
The opportunity also emphasizes a modern view of translation as a two-way process rather than a simple pipeline from "bench to bedside." Investigators are urged not to treat translational research as a one-direction handoff where basic science finishes and clinical work begins. Instead, proposals are expected to reflect a reciprocal flow of ideas between basic and clinical science. That could mean clinical findings shaping lab experiments, lab results refining clinical study design, or iterative feedback loops where early testing informs additional mechanistic work and vice versa. Projects that build these back-and-forth connections into the research plan are described as highly encouraged, which signals that the review process is likely to favor teams and designs that genuinely integrate clinical and laboratory perspectives.
From an administrative standpoint, the award is offered by the Department of Defense, Department of the Army, through USAMRAA, and is categorized as discretionary funding under the Science and Technology and other Research and Development umbrella (CFDA 12.420). Funding instruments include both grants and cooperative agreements, which typically means applicants should be prepared for either a more standard grant relationship or a cooperative structure where the sponsor may have substantial involvement in project oversight or coordination. Eligibility is listed as unrestricted, indicating that a wide range of organization types may apply, subject to any additional constraints that might appear in the full announcement. The funding listing anticipated about three awards, with an award ceiling listed as 0 in the provided data, which usually suggests that applicants should rely on the full solicitation for specific budget limits or that the ceiling was not specified in the summary record. The opportunity was created May 30, 2018, with an original closing date of November 8, 2018.
Overall, this award targets teams that can credibly demonstrate a near- to mid-term pathway to clinical impact in hearing restoration, backed by a translational plan that actively connects discovery work with clinical application. The strongest fit is research that does more than generate knowledge: it intentionally reduces the distance between an observation and a practical intervention, tool, or guideline that can change how hearing loss or auditory damage is addressed in clinical settings.Apply for W81XWH 18 HRRP TRA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Hearing Restoration Translational Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on May 30, 2018.
- Applicants must submit their applications by Nov 08, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs): DoD Hearing Restoration Translational Research Award (FY18 HRRP TRA)
What is the DoD Hearing Restoration Translational Research Award (FY18 HRRP TRA)?
The FY18 HRRP Translational Research Award (Funding Opportunity Number W81XWH 18 HRRP TRA) is a Department of Defense funding opportunity focused on moving hearing restoration science from research settings into real-world clinical use. It is aimed at projects with credible, promising findings that are ready to be advanced toward practical applications that can be tested, validated, and used to improve patient care.
What kind of research is this award meant to support?
This opportunity sits in the translational space. It is meant to accelerate work that turns promising observations into clinically relevant outcomes, such as healthcare products, enabling technologies, or evidence-based practice guidelines that clinicians can implement. The intent is not to fund purely exploratory basic science, but to shorten the path between discovery and clinical impact.
Does the program fund basic science projects?
The opportunity emphasizes translation over purely exploratory basic research. Projects are expected to focus on steps that move hearing-related discoveries toward applications that can be evaluated and used in clinical practice, rather than work that is primarily aimed at generating foundational knowledge without a clear route to clinical use.
What does “translational research” mean in this program?
In this program, translational research is framed as intentionally reducing the distance between an observation and a practical intervention, tool, technology, or guideline that can change patient care. It also reflects a two-way process where clinical and laboratory work inform each other rather than a one-direction “bench to bedside” handoff.
What are acceptable starting points for a translational project under this award?
The DoD explicitly recognizes multiple valid starting points for impactful translational ideas. A project can begin from laboratory breakthroughs, population-level or epidemiologic findings, practical clinical insights, and even well-grounded anecdotal experience, as long as the proposal is structured to convert those observations into actionable, clinically relevant outcomes.
Does the award encourage collaboration between clinical and laboratory teams?
Yes. Proposals are expected to reflect reciprocal, back-and-forth connections between basic and clinical science. Designs that incorporate iterative feedback loops (for example, clinical findings shaping lab experiments and lab results refining clinical study plans) are described as highly encouraged.
Is translational research expected to be a one-way “bench to bedside” pipeline?
No. The opportunity emphasizes a modern, two-way view of translation. Investigators are urged to design projects where clinical and basic science continually inform each other, rather than treating translation as a simple sequence where basic research ends and clinical work begins.
Who is offering and administering this funding opportunity?
The award is offered by the Department of Defense, Department of the Army, through USAMRAA (as described in the provided opportunity information).
What is the CFDA number associated with this opportunity?
The opportunity is listed under CFDA 12.420, categorized under the “Science and Technology and other Research and Development” umbrella.
What funding instruments are used for this award?
The listing indicates that funding instruments include grants and cooperative agreements. This means applicants should be prepared for either a standard grant structure or a cooperative arrangement where the sponsor may have substantial involvement in oversight or coordination.
What does it mean that the award can be a cooperative agreement?
Based on the opportunity description, a cooperative agreement typically implies greater sponsor involvement in project oversight or coordination compared with a standard grant. The listing suggests applicants should be ready for either structure.
Who is eligible to apply?
Eligibility is listed as unrestricted in the provided information, indicating a wide range of organization types may apply, subject to any additional constraints that might appear in the full announcement.
How many awards were anticipated?
The funding listing anticipated about three awards.
What is the award ceiling or maximum budget?
The award ceiling is listed as 0 in the provided data. This commonly indicates the ceiling was not specified in the summary record, or that applicants should rely on the full solicitation for specific budget limits and constraints.
When was the opportunity created and when did it close?
The opportunity was created on May 30, 2018, with an original closing date of November 8, 2018.
What types of outcomes are considered a strong fit for this award?
Strong-fit projects are those that intentionally move a hearing restoration discovery or observation toward clinical impact, such as developing healthcare products, enabling technologies, or evidence-based practice guidelines that can be implemented in clinical settings.
What will reviewers likely look for in a competitive proposal?
Based on the emphasis in the description, competitive proposals will likely demonstrate: (1) credible and promising findings or observations as a foundation, (2) a near- to mid-term pathway to clinical impact, and (3) a translational plan that integrates clinical and laboratory perspectives through reciprocal feedback between discovery and application.
Can clinically driven needs or constraints be the basis for innovation in this program?
Yes. The opportunity encourages applicants to treat patient needs and real clinical constraints as legitimate starting points for innovation, provided the project is structured to produce actionable, clinically relevant outputs.
Is the program focused on generating knowledge or changing practice?
The description emphasizes that the strongest fit is research that goes beyond generating knowledge and actively reduces the distance to practical interventions, tools, technologies, or guidelines that can change how hearing loss or auditory damage is addressed in clinical settings.
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